|Other Accession||NM_018093, NP_060563|
|Reactivity||Human, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Predicted||Human, Rat, Rabbit, Horse, Bovine, Dog|
|Alias Symbol||FLJ10439, FLJ21730|
|Other Names||WD repeat-containing protein 74, NOP seven-associated protein 1, WDR74, NSA1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-WDR74 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||WDR74 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit (PubMed:26456651). Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL (PubMed:29107693). Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development (By similarity).|
|Cellular Location||Nucleus, nucleolus. Nucleus Note=Nucleolar location depends on active PolI transcription of pre- rRNA.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Eilbracht J.,et al.Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherl A.,et al.Mol. Biol. Cell 13:4100-4109(2002).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Olsen J.V.,et al.Sci. Signal. 3:RA3-RA3(2010).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.