|Other Accession||NM_012452, NP_036584|
|Reactivity||Human, Mouse, Rat, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Rat, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||CD267, CVID, FLJ39942, MGC133214, MGC39952, TACI, TNFRSF14B, CVID2|
|Other Names||Tumor necrosis factor receptor superfamily member 13B, Transmembrane activator and CAML interactor, CD267, TNFRSF13B, TACI|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-TNFRSF13B antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||TNFRSF13B antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin- dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.|
|Cellular Location||Membrane; Single-pass type III membrane protein.|
|Tissue Location||Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B-cells and activated T-cells, but not in resting T-cells|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
von Buelow G.-U.,et al.Science 278:138-141(1997).
Zhou G.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Wu Y.,et al.J. Biol. Chem. 275:35478-35485(2000).
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