TNFRSF13B antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
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Primary Accession | O14836 |
Other Accession | NM_012452, NP_036584 |
Reactivity | Human, Mouse, Rat, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Rat, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 32kDa |
Gene ID | 23495 |
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Alias Symbol | CD267, CVID, FLJ39942, MGC133214, MGC39952, TACI, TNFRSF14B, CVID2 |
Other Names | Tumor necrosis factor receptor superfamily member 13B, Transmembrane activator and CAML interactor, CD267, TNFRSF13B, TACI |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-TNFRSF13B antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | TNFRSF13B antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TNFRSF13B |
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Synonyms | TACI |
Function | Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin- dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. |
Cellular Location | Membrane; Single-pass type III membrane protein. |
Tissue Location | Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B-cells and activated T-cells, but not in resting T-cells |

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Provided below are standard protocols that you may find useful for product applications.
References
von Buelow G.-U.,et al.Science 278:138-141(1997).
Zhou G.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Wu Y.,et al.J. Biol. Chem. 275:35478-35485(2000).

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