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TNFRSF13B / TACI Antibody (aa116-132)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, FC |
|---|---|
| Primary Accession | O14836 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 32kDa |
| Dilution | IHC-P (5 µg/ml), WB (5 µg/ml), |
| Gene ID | 23495 |
|---|---|
| Other Names | Tumor necrosis factor receptor superfamily member 13B, Transmembrane activator and CAML interactor, CD267, TNFRSF13B, TACI |
| Target/Specificity | A synthetic peptide corresponding to amino acids 116-132 of human TACI. Human and mouse TACI amino acid sequences are 65% conserved in the immunogen. |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | TNFRSF13B / TACI Antibody (aa116-132) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TNFRSF13B |
|---|---|
| Synonyms | TACI |
| Function | Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin- dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. |
| Cellular Location | Membrane; Single-pass type III membrane protein. |
| Tissue Location | Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B-cells and activated T-cells, but not in resting T-cells |
| Volume | 1 ea |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T- cell function and the regulation of humoral immunity.
References
von Buelow G.-U.,et al.Science 278:138-141(1997).
Zhou G.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Wu Y.,et al.J. Biol. Chem. 275:35478-35485(2000).
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