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HCRTR1 antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - HCRTR1 antibody - C-terminal region AI15214

    Host: Rabbit
    Target Name: HCRTR1
    Antibody Dilution: 1.0μg/ml
    Sample Tissue: Human brain
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession O43613
Other Accession NM_001525, NP_001516
Reactivity Human, Rabbit, Horse
Predicted Human, Rabbit, Horse
Host Rabbit
Clonality Polyclonal
Calculated MW 47kDa
Additional Information
Gene ID 3061
Alias Symbol OX1R
Other Names Orexin receptor type 1, Ox-1-R, Ox1-R, Ox1R, Hypocretin receptor type 1, HCRTR1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-HCRTR1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsHCRTR1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HCRTR1 (HGNC:4848)
Function Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide (PubMed:9491897, PubMed:26950369). Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding (PubMed:9491897, PubMed:26950369).
Cellular Location Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)
citation

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References

Sakurai T.,et al.Cell 92:573-585(1998).
Peyron C.,et al.Nat. Med. 6:991-997(2000).
Olafsdottir B.R.,et al.Neurology 57:1896-1899(2001).
Yeager M.,et al.Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 389.00
Cat# AI15214
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