Spaca3 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9D9X8 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Goat, Sheep, Horse, Bovine, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Goat, Sheep, Horse, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 24kDa |
Gene ID | 75622 |
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Other Names | Sperm acrosome membrane-associated protein 3, Lysozyme-like protein 3, Sperm lysozyme-like protein 1, mSLLP1, Sperm acrosome membrane-associated protein 3, membrane form, Sperm acrosome membrane-associated protein 3, processed form, Spaca3, Lyc3, Lyzl3, Sllp1 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Spaca3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Spaca3 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Spaca3 |
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Synonyms | Lyc3, Lyzl3, Sllp1 |
Function | Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N- acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro (By similarity). |
Cellular Location | Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Single-pass type II membrane protein. Note=Anterior acrosome in non- capacitated spermatozoa and retained in the equatorial segment and in the luminal face of both the inner and outer acrosomal membranes following capacitation and the acrosome reaction |
Tissue Location | The processed form is expressed in sperm (at protein level). Expressed strongly in testis and epididymis and weakly in pancreas. |
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Provided below are standard protocols that you may find useful for product applications.
References
Zhang K.,et al.Biol. Reprod. 73:1064-1071(2005).
Carninci P.,et al.Science 309:1559-1563(2005).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Herrero M.B.,et al.Dev. Biol. 284:126-142(2005).
Sachdev M.,et al.Dev. Biol. 363:40-51(2012).
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