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SMTNL1 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | A8MU46 |
| Reactivity | Human, Pig, Yeast, Dog |
| Predicted | Human, Pig, Yeast, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 50kDa |
| Gene ID | 219537 |
|---|---|
| Other Names | Smoothelin-like protein 1, SMTNL1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 &mu, l of distilled water. Final Anti-SMTNL1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | SMTNL1 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SMTNL1 |
|---|---|
| Function | Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-299 reduces this inhibitory activity (By similarity). |
| Cellular Location | Cytoplasm, myofibril. Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, myofibril, sarcomere, M line Nucleus. Note=Colocalizes with MYH2. In its unphosphorylated state, localizes to the cytoplasm (By similarity) Phosphorylation at Ser-301 promotes translocation to the nucleus (By similarity). |
| Tissue Location | Expressed in striated muscles, specifically in type 2a fibers (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Taylor T.D.,et al.Nature 440:497-500(2006).
Wooldridge A.A.,et al.J. Biol. Chem. 283:11850-11859(2008).
Lontay B.,et al.J. Biol. Chem. 285:29357-29366(2010).
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