SMTNL1 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | A8MU46 |
Reactivity | Human, Pig, Yeast, Dog |
Predicted | Human, Pig, Yeast, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 50kDa |
Gene ID | 219537 |
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Other Names | Smoothelin-like protein 1, SMTNL1 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 &mu, l of distilled water. Final Anti-SMTNL1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
Precautions | SMTNL1 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SMTNL1 |
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Function | Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-299 reduces this inhibitory activity (By similarity). |
Cellular Location | Cytoplasm, myofibril. Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, myofibril, sarcomere, M line Nucleus. Note=Colocalizes with MYH2. In its unphosphorylated state, localizes to the cytoplasm (By similarity) Phosphorylation at Ser-301 promotes translocation to the nucleus (By similarity). |
Tissue Location | Expressed in striated muscles, specifically in type 2a fibers (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
References
Taylor T.D.,et al.Nature 440:497-500(2006).
Wooldridge A.A.,et al.J. Biol. Chem. 283:11850-11859(2008).
Lontay B.,et al.J. Biol. Chem. 285:29357-29366(2010).
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