|Other Accession||NM_178422, NP_848509|
|Reactivity||Human, Mouse, Rat, Horse, Guinea Pig|
|Predicted||Human, Mouse, Rat, Pig, Horse, Guinea Pig|
|Alias Symbol||MPRA, PGLP, mSR|
|Other Names||Membrane progestin receptor alpha, mPR alpha, Progestin and adipoQ receptor family member 7, Progestin and adipoQ receptor family member VII, PAQR7, MRPA|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-PAQR7 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PAQR7 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432). Seems to act through a G(i) mediated pathway (PubMed:23763432). May be involved in oocyte maturation (PubMed:12601167). Involved in neurosteroid inhibition of apoptosis (PubMed:23161870). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23161870).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in a wide range of tissues including ovary, testis, placenta, uterus and bladder|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Zhu Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:2237-2242(2003).
Tang Y.T.,et al.J. Mol. Evol. 61:372-380(2005).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Hammes S.R.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:2168-2170(2003).
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