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PAQR7 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q86WK9 |
| Other Accession | NP_848509.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 39719 Da |
| Antigen Region | 281-310 aa |
| Gene ID | 164091 |
|---|---|
| Other Names | Membrane progestin receptor alpha, mPR alpha, Progestin and adipoQ receptor family member 7, Progestin and adipoQ receptor family member VII, PAQR7, MRPA |
| Target/Specificity | This PAQR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-310 amino acids from the C-terminal region of human PAQR7. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PAQR7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PAQR7 (HGNC:23146) |
|---|---|
| Synonyms | MRPA |
| Function | Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432). Seems to act through a G(i) mediated pathway (PubMed:23763432). May be involved in oocyte maturation (PubMed:12601167). Involved in neurosteroid inhibition of apoptosis (PubMed:23161870). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23161870). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in a wide range of tissues including ovary, testis, placenta, uterus and bladder |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
PAQR7 is a steroid membrane receptor. Binds progesterone in vitro. It may be involved in oocyte maturation.
References
Thomas, P., et al. Steroids 74(7):614-621(2009)
Smith, J.L., et al. Steroids 73(11):1160-1173(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Thomas, P., et al. Endocrinology 148(2):705-718(2007)
Tang, Y.T., et al. J. Mol. Evol. 61(3):372-380(2005)
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