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CDK10 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q15131 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 39kDa |
| Gene ID | 8558 |
|---|---|
| Alias Symbol | CDK10, |
| Other Names | Cyclin-dependent kinase 10, 2.7.11.22, Cell division protein kinase 10, Serine/threonine-protein kinase PISSLRE, CDK10 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 &mu, l of distilled water. Final Anti-CDK10 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | CDK10 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CDK10 |
|---|---|
| Function | Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells) (PubMed:24218572). Involved in the regulation of actin cytoskeleton organization through the phosphorylation of actin dynamics regulators such as PKN2. Is a negative regulator of ciliogenesis through phosphorylation of PKN2 and promotion of RhoA signaling (PubMed:27104747). |
| Cellular Location | Cytoplasm, cytoskeleton, cilium basal body |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells).
References
Grana X.,et al.Oncogene 9:2097-2103(1994).
Grana X.,et al.Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
Brambilla R.,et al.Oncogene 9:3037-3041(1994).
Crawford J.,et al.Genomics 56:90-97(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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