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GRM8 / MGLUR8 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | O00222 |
| Reactivity | Human, Mouse, Monkey, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 102kDa |
| Dilution | IHC-P (7-18 µg/ml) |
| Gene ID | 2918 |
|---|---|
| Other Names | Metabotropic glutamate receptor 8, mGluR8, GRM8, GPRC1H, MGLUR8 |
| Target/Specificity | Human GRM8 / MGLUR8. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | GRM8 / MGLUR8 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GRM8 |
|---|---|
| Synonyms | GPRC1H, MGLUR8 |
| Function | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
References
Scherer S.W.,et al.Genomics 44:232-236(1997).
Wu S.,et al.Brain Res. Mol. Brain Res. 53:88-97(1998).
Malherbe P.,et al.Brain Res. Mol. Brain Res. 67:201-210(1999).
Stormann T.M.,et al.Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
Kaighin V.A.,et al.Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
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