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ADGRB2 / BAI2 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | O60241 |
| Reactivity | Human, Monkey, Guinea Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 173kDa |
| Dilution | IHC-P (10 µg/ml) |
| Gene ID | 576 |
|---|---|
| Other Names | Brain-specific angiogenesis inhibitor 2, BAI2 |
| Target/Specificity | Human BAI2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PNMAL1 (53%). |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | ADGRB2 / BAI2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ADGRB2 (HGNC:944) |
|---|---|
| Synonyms | BAI2 |
| Function | Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT-signaling pathway, a transcription factor, via the G-protein GNAZ (PubMed:20367554, PubMed:28891236). Involved in angiogenesis inhibition (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Secreted |
| Tissue Location | Detected in cerebrospinal fluid (at protein level) (PubMed:25326458). Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Might be involved in angiogenesis inhibition.
References
Shiratsuchi T.,et al.Cytogenet. Cell Genet. 79:103-108(1997).
Suwa M.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
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