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GPR87 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | Q9BY21 |
| Reactivity | Human, Rabbit, Hamster, Monkey, Pig, Horse, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 41kDa |
| Dilution | IHC-P (6-14 µg/ml) |
| Gene ID | 53836 |
|---|---|
| Other Names | G-protein coupled receptor 87, G-protein coupled receptor 95, GPR87, GPR95 |
| Target/Specificity | Human GPR87. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except YSK4 (63%). |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | GPR87 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GPR87 |
|---|---|
| Synonyms | GPR95 |
| Function | Receptor for lysophosphatidic acid (LPA) (PubMed:17905198). Necessary for p53/TP53-dependent survival in response to DNA damage (PubMed:19602589). Promotes the Hippo-YAP signaling pathway and thereby modulates glycolysis and oxidative stress production by the regulation of hexokinase-2/HK2 (PubMed:35843477). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in placenta and prostate. Weaker expression in thymus. Not expressed in thalamus, hippocampus, pons or cerebellum. Overexpressed in squamous cell carcinoma of the lung |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage.
References
Urakawa I.,et al.Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.
Lee D.K.,et al.Gene 275:83-91(2001).
Wittenberger T.,et al.J. Mol. Biol. 307:799-813(2001).
Kaighin V.A.,et al.Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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