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GPR87 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9BY21 |
| Other Accession | Q99MT7, NP_076404.3 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 41436 Da |
| Antigen Region | 329-357 aa |
| Gene ID | 53836 |
|---|---|
| Other Names | G-protein coupled receptor 87, G-protein coupled receptor 95, GPR87, GPR95 |
| Target/Specificity | This GPR87 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-357 amino acids from the C-terminal region of human GPR87. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GPR87 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GPR87 |
|---|---|
| Synonyms | GPR95 |
| Function | Receptor for lysophosphatidic acid (LPA) (PubMed:17905198). Necessary for p53/TP53-dependent survival in response to DNA damage (PubMed:19602589). Promotes the Hippo-YAP signaling pathway and thereby modulates glycolysis and oxidative stress production by the regulation of hexokinase-2/HK2 (PubMed:35843477). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in placenta and prostate. Weaker expression in thymus. Not expressed in thalamus, hippocampus, pons or cerebellum. Overexpressed in squamous cell carcinoma of the lung |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
G protein-coupled receptors play a role in cell communication. They are characterized by an extracellular N terminus, 7 transmembrane regions, and an intracellular C terminus.
References
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
Zhang, Y., et al. Cancer Res. 69(15):6049-6056(2009)
Glatt, S., et al. Int. J. Cancer 122(9):2008-2016(2008)
Gugger, M., et al. Dis. Markers 24(1):41-50(2008)
Tabata, K., et al. Biochem. Biophys. Res. Commun. 363(3):861-866(2007)
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