|Reactivity||Human, Rabbit, Monkey, Pig, Dog|
|Dilution||IHC-P (10-20 µg/ml)|
|Other Names||Probable G-protein coupled receptor 133, G-protein coupled receptor PGR25, GPR133, PGR25|
|Target/Specificity||Human GPR133. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||ADGRD1 / GPR133 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Orphan receptor. Signals via G(s)-alpha family of G-proteins (PubMed:22025619, PubMed:22575658). Has protumorigenic function especially in glioblastoma (PubMed:27775701).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Up-regulated in CD133(+) cell population of glioblastoma.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Bonner T.I.,et al.Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
Bjarnadottir T.K.,et al.Genomics 84:23-33(2004).
Bonner T.I.,et al.Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
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