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GPR133 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q6QNK2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 96530 Da |
| Antigen Region | 471-498 aa |
| Gene ID | 283383 |
|---|---|
| Other Names | Probable G-protein coupled receptor 133, G-protein coupled receptor PGR25, GPR133, PGR25 |
| Target/Specificity | This GPR133 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 471-498 amino acids from the Central region of human GPR133. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GPR133 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ADGRD1 |
|---|---|
| Synonyms | GPR133, PGR25 |
| Function | Orphan receptor. Signals via G(s)-alpha family of G-proteins (PubMed:22025619, PubMed:22575658). Has protumorigenic function especially in glioblastoma (PubMed:27775701). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Up-regulated in CD133(+) cell population of glioblastoma. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
GPR133 is an orphan receptor.
References
Tonjes, A., et al. Hum. Mol. Genet. 18(23):4662-4668(2009)
Marroni, F., et al. Circ Cardiovasc Genet 2(4):322-328(2009)
Otowa, T., et al. J. Hum. Genet. 54(2):122-126(2009)
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