FSH Receptor / FSHR Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | P23945 |
Reactivity | Human, Monkey |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 78kDa |
Dilution | IHC-P (7-14 µg/ml) |
Gene ID | 2492 |
---|---|
Other Names | Follicle-stimulating hormone receptor, FSH-R, Follitropin receptor, FSHR, LGR1 |
Target/Specificity | Human FSHR. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
Precautions | FSH Receptor / FSHR Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FSHR |
---|---|
Synonyms | LGR1 |
Function | G protein-coupled receptor for follitropin, the follicle- stimulating hormone (PubMed:11847099, PubMed:24058690, PubMed:24692546). Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways (PubMed:24058690). |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Sertoli cells and ovarian granulosa cells. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
References
Minegish T.,et al.Biochem. Biophys. Res. Commun. 175:1125-1130(1991).
Tilly J.L.,et al.Endocrinology 131:799-806(1992).
Kelton C.A.,et al.Mol. Cell. Endocrinol. 89:141-151(1992).
Liu X.,et al.Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
Kopatz S.A.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
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