|Dilution||IHC-P (7-14 µg/ml)|
|Other Names||Follicle-stimulating hormone receptor, FSH-R, Follitropin receptor, FSHR, LGR1|
|Target/Specificity||Human FSHR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||FSH Receptor / FSHR Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||G protein-coupled receptor for follitropin, the follicle- stimulating hormone (PubMed:11847099, PubMed:24058690, PubMed:24692546). Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways (PubMed:24058690).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Sertoli cells and ovarian granulosa cells.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Minegish T.,et al.Biochem. Biophys. Res. Commun. 175:1125-1130(1991).
Tilly J.L.,et al.Endocrinology 131:799-806(1992).
Kelton C.A.,et al.Mol. Cell. Endocrinol. 89:141-151(1992).
Liu X.,et al.Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
Kopatz S.A.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
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