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XPR1 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, ICC |
|---|---|
| Primary Accession | Q9UBH6 |
| Reactivity | Human, Mouse, Rabbit, Hamster, Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 82kDa |
| Dilution | IHC-P (8 µg/ml) |
| Gene ID | 9213 |
|---|---|
| Other Names | Xenotropic and polytropic retrovirus receptor 1, Protein SYG1 homolog, Xenotropic and polytropic murine leukemia virus receptor X3, X-receptor, XPR1, SYG1, XR |
| Target/Specificity | Human XPR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | XPR1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | XPR1 {ECO:0000303|PubMed:31043717} |
|---|---|
| Function | Inorganic ion transporter that mediates phosphate ion export across plasma membrane. Plays a major role in phosphate homeostasis, preventing intracellular phosphate accumulation and possible calcium phosphate precipitation, ultimately preserving calcium signaling. The molecular mechanism of phosphate transport, whether electrogenic, electroneutral or coupled to other ions, remains to be elucidated (PubMed:23791524, PubMed:25938945, PubMed:31043717) (By similarity). Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5- InsP7), important intracellular signaling molecules involved in regulation of phosphate flux (PubMed:27080106). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Widely expressed. Detected in spleen, lymph node, thymus, leukocytes, bone marrow, heart, kidney, pancreas and skeletal muscle. |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
May function in G-protein coupled signal transduction (By similarity). Potential receptor for xenotropic and polytropic murine leukemia retroviruses.
References
Yang Y.-L.,et al.Nat. Genet. 21:216-219(1999).
Tailor C.S.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:927-932(1999).
Battini J.-L.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:1385-1390(1999).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
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