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OR10J5 Antibody (Extracellular Domain)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | Q8NHC4 |
| Reactivity | Human, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 34kDa |
| Dilution | IHC-P (15 µg/ml) |
| Gene ID | 127385 |
|---|---|
| Other Names | Olfactory receptor 10J5, Olfactory receptor OR1-28, OR10J5 |
| Target/Specificity | Human OR10J5. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except OR10J6P (63%). |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | OR10J5 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | OR10J5 (HGNC:14993) |
|---|---|
| Function | Olfactory receptor. Activated by the synthetic floral odorant, lyral, and by alpha-cedrene, a sesquiterpene constituent of cedarwood oil. Its activation increases intracellular Ca(2+) (PubMed:25791473, PubMed:28842679). Acts as a key regulator of myogenesis through its actions on cell migration and adhesion by activating the Ca(2+)-dependent AKT signal transduction pathway (By similarity). Also acts as a regulator of angiogenesis (PubMed:25791473). Moreover, plays a role in the regulation of lipid accumulation in hepatocytes via the cAMP-PKA pathway (PubMed:28842679). May be involved in sperm chemotaxis and motility (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in both the aorta, the coronary artery and umbilical vein endothelial cells (HUVECs) (at protein level) |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Odorant receptor.
References
Suwa M.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Malnic B.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:2584-2589(2004).
Malnic B.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:7205-7205(2004).
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