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TACR3 / NK3R Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | P29371 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 52kDa |
| Dilution | IHC-P (20 µg/ml) |
| Gene ID | 6870 |
|---|---|
| Other Names | Neuromedin-K receptor, NKR, NK-3 receptor, NK-3R, Neurokinin B receptor, Tachykinin receptor 3, TACR3, NK3R, TAC3R |
| Target/Specificity | Human TACR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
| Precautions | TACR3 / NK3R Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TACR3 |
|---|---|
| Synonyms | NK3R, TAC3R |
| Function | This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.
References
Huang R.-R.C.,et al.Biochem. Biophys. Res. Commun. 184:966-972(1992).
Buell G.,et al.FEBS Lett. 299:90-95(1992).
Takahashi K.,et al.Eur. J. Biochem. 204:1025-1033(1992).
Kopatz S.A.,et al.Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
Topaloglu A.K.,et al.Nat. Genet. 41:354-358(2009).
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