TLR10 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | Q9BXR5 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 95kDa |
Dilution | IHC-P (2.5 µg/ml) |
Gene ID | 81793 |
---|---|
Other Names | Toll-like receptor 10, CD290, TLR10 |
Reconstitution & Storage | +4°C or -20°C, Avoid repeated freezing and thawing. |
Precautions | TLR10 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TLR10 |
---|---|
Function | Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). |
Cellular Location | Membrane; Single-pass type I membrane protein |
Tissue Location | Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
References
Chuang T.-H.,et al.Biochim. Biophys. Acta 1518:157-161(2001).
Nakajima T.,et al.Immunogenetics 60:727-735(2008).
Georgel P.,et al.PLoS ONE 4:E7803-E7803(2009).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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