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ARHGEF11 Antibody (aa1-50)

Rabbit Polyclonal Antibody

     
  • IHC - ARHGEF11 Antibody (aa1-50) ALS11932
    Anti-ARHGEF11 antibody IHC of human skin.
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession O15085
Reactivity Human, Mouse, Rat, Monkey, Chicken, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 168kDa
Dilution IHC-P (10 µg/ml), WB (0.1-0.5 µg/ml),
Additional Information
Gene ID 9826
Other Names Rho guanine nucleotide exchange factor 11, PDZ-RhoGEF, ARHGEF11, KIAA0380
Target/Specificity A portion of amino acids 1-50 of human ARHGEF11
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsARHGEF11 Antibody (aa1-50) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARHGEF11
Synonyms KIAA0380
Function May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth.
Cellular Location Cytoplasm. Membrane. Note=Translocated to the membrane upon stimulation
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)
citation

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Background

May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth.

References

Nagase T.,et al.DNA Res. 4:141-150(1997).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Ruemenapp U.,et al.FEBS Lett. 459:313-318(1999).
Fukuhara S.,et al.J. Biol. Chem. 274:5868-5879(1999).

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$ 467.50
Cat# ALS11932
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