EFHD2 Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC-P, IF, E |
---|---|
Primary Accession | Q96C19 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 27kDa |
Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
Gene ID | 79180 |
---|---|
Other Names | EF-hand domain-containing protein D2, Swiprosin-1, EFHD2, SWS1 |
Target/Specificity | Human EFHD2 |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | EFHD2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | EFHD2 |
---|---|
Synonyms | SWS1 |
Function | May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. |
Cellular Location | Membrane raft. Note=In a mouse immature B-cell line WEHI-231. |
Tissue Location | Found in lymphocytes; preferentially expressed in CD8+ cells. |

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Background
May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
References
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Bienvenut W.V.,et al.Submitted (FEB-2008) to UniProtKB.
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
Vuadens F.,et al.Proteomics 2:105-111(2002).

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