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LASP1 Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q14847 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 30kDa |
| Dilution | ELISA (1:32000), IHC-P (2.5-5 µg/ml), WB (1:32000) |
| Gene ID | 3927 |
|---|---|
| Other Names | LIM and SH3 domain protein 1, LASP-1, Metastatic lymph node gene 50 protein, MLN 50, LASP1, MLN50 |
| Target/Specificity | Human LASP1. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | LASP1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LASP1 |
|---|---|
| Synonyms | MLN50 |
| Function | Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). |
| Cellular Location | Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Note=Associated with the F-actin rich cortical cytoskeleton. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity).
References
Tomasetto C.L.,et al.Genomics 28:367-376(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Gevaert K.,et al.Nat. Biotechnol. 21:566-569(2003).
Tomasetto C.,et al.FEBS Lett. 373:245-249(1995).
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