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LASP1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q14847 |
| Other Accession | NP_006139.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 29717 Da |
| Antigen Region | 120-148 aa |
| Gene ID | 3927 |
|---|---|
| Other Names | LIM and SH3 domain protein 1, LASP-1, Metastatic lymph node gene 50 protein, MLN 50, LASP1, MLN50 |
| Target/Specificity | This LASP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-148 amino acids from the Central region of human LASP1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | LASP1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LASP1 |
|---|---|
| Synonyms | MLN50 |
| Function | Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). |
| Cellular Location | Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Note=Associated with the F-actin rich cortical cytoskeleton. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of a LIM protein subfamily characterized by a LIM motif and a domain of Src homology region 3. The encoded protein functions as an actin-binding protein and possibly in cytoskeletal organization.
References
Traenka, C., et al. Cancer Res. 70(20):8003-8014(2010)
Zhao, L., et al. FEBS J. 277(20):4195-4204(2010)
Zhao, L., et al. Gut 59(9):1226-1235(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Frietsch, J.J., et al. Br. J. Cancer 102(11):1645-1653(2010)
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