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SERPING1 / C1 Inhibitor Antibody (clone 3F4-1D9)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E, IP |
|---|---|
| Primary Accession | P05155 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 3F4-1D9 |
| Calculated MW | 55kDa |
| Dilution | IHC-P (5 µg/ml), WB (1:500-1:1000), |
| Gene ID | 710 |
|---|---|
| Other Names | Plasma protease C1 inhibitor, C1 Inh, C1Inh, C1 esterase inhibitor, C1-inhibiting factor, Serpin G1, SERPING1, C1IN, C1NH |
| Target/Specificity | Human SERPING1 |
| Reconstitution & Storage | Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles. |
| Precautions | SERPING1 / C1 Inhibitor Antibody (clone 3F4-1D9) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SERPING1 |
|---|---|
| Synonyms | C1IN, C1NH |
| Function | Activation of the C1 complex is under control of the C1- inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. |
| Cellular Location | Secreted. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Activation of the C1 complex is under control of the C1- inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein.
References
Que B.G.,et al.Biochem. Biophys. Res. Commun. 137:620-625(1986).
Bock S.C.,et al.Biochemistry 25:4292-4301(1986).
Carter P.E.,et al.Eur. J. Biochem. 173:163-169(1988).
Carter P.E.,et al.Eur. J. Biochem. 197:301-308(1991).
Heus J.,et al.Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
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