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HSPB6 / HSP20 Antibody (aa5-54)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, E |
|---|---|
| Primary Accession | O14558 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 17kDa |
| Dilution | ELISA (1:5000), IHC-P (10 µg/ml), |
| Gene ID | 126393 |
|---|---|
| Other Names | Heat shock protein beta-6, HspB6, Heat shock 20 kDa-like protein p20, HSPB6 |
| Target/Specificity | HSPB6 antibody detects endogenous levels of total HSPB6 protein. |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | HSPB6 / HSP20 Antibody (aa5-54) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HSPB6 |
|---|---|
| Function | Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity. |
| Cellular Location | Cytoplasm. Nucleus. Secreted Note=Translocates to nuclear foci during heat shock |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).
Kato K.,et al.J. Biol. Chem. 269:15302-15309(1994).
Vos M.J.,et al.Biochim. Biophys. Acta 1793:1343-1353(2009).
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