LMX1B Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF |
---|---|
Primary Accession | O60663 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 45kDa |
Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
Gene ID | 4010 |
---|---|
Other Names | LIM homeobox transcription factor 1-beta, LIM/homeobox protein 1.2, LMX-1.2, LIM/homeobox protein LMX1B, LMX1B |
Target/Specificity | Human LMX1B. At least three isoforms are known to exist. This antibody is predicted to not cross-react with LMX1A. |
Reconstitution & Storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
Precautions | LMX1B Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LMX1B |
---|---|
Function | Transcription factor involved in the regulation of podocyte- expressed genes (PubMed:24042019, PubMed:28059119). Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels. |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. |
Tissue Location | Expressed in most tissues. Highest levels in testis, thyroid, duodenum, skeletal muscle, and pancreatic islets |
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Provided below are standard protocols that you may find useful for product applications.
Background
Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels.
References
Vollrath D.,et al.Hum. Mol. Genet. 7:1091-1098(1998).
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Dreyer S.D.,et al.Nat. Genet. 19:47-50(1998).
McIntosh I.,et al.Am. J. Hum. Genet. 63:1651-1658(1998).
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