ADAM19 Antibody (aa574-588)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC-P, E |
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Primary Accession | Q9H013 |
Reactivity | Human, Rabbit, Monkey, Pig, Bovine |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 105kDa |
Dilution | ELISA (1:128000), IHC-P (5 µg/ml), WB (0.1-0.3 µg/ml) |
Gene ID | 8728 |
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Other Names | Disintegrin and metalloproteinase domain-containing protein 19, ADAM 19, 3.4.24.-, Meltrin-beta, Metalloprotease and disintegrin dendritic antigen marker, MADDAM, ADAM19, MLTNB |
Target/Specificity | Human ADAM19 |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | ADAM19 Antibody (aa574-588) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ADAM19 |
---|---|
Synonyms | MLTNB |
Function | Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity). |
Cellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Location | Expressed in many normal organ tissues and several cancer cell lines |

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Background
Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity).
References
Wang Y.-G.,et al.Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases.
Fritsche J.,et al.Blood 96:732-739(2000).
Wei P.,et al.Biochem. Biophys. Res. Commun. 280:744-755(2001).
Schmutz J.,et al.Nature 431:268-274(2004).
Xu R.,et al.Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.

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