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KCNK12 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | Q9HB15 |
| Other Accession | 56660 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 46889 Da |
| Dilution | IF (20 µg/ml), IHC-P (5 µg/ml), WB (1 - 2 µg/ml), |
| Gene ID | 56660 |
|---|---|
| Other Names | KCNK12, K2p12.1, THIK-2, THIK2 |
| Target/Specificity | Human KCNK12. KCNK12 antibody is predicted to not cross-react with other KCNK protein family members. |
| Reconstitution & Storage | PBS, 0.02% sodium azide. Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Precautions | KCNK12 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KCNK12 {ECO:0000303|PubMed:24163367, ECO:0000312|HGNC:HGNC:6274} |
|---|---|
| Function | K(+) channel subunit that may homo- and heterodimerize to form functional channels with distinct regulatory and gating properties. Can heterodimerize with KCNK13 subunit to conduct K(+) outward rectifying currents at the plasma membrane. The homodimers are mainly retained in the endoplasmic reticulum compartment and may be targeted to the cell surface upon phosphorylation or other activation signals yet to be elucidated. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel (By similarity).
References
Rajan S.,et al.J. Biol. Chem. 276:7302-7311(2001).
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