SLC35D3 / FRCL1 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, IHC-P, IF, ICC, E |
|---|---|
| Primary Accession | Q5M8T2 |
| Other Accession | 340146 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 44183 Da |
| Dilution | ICC (2.5 µg/ml), IF (5 µg/ml), IHC-P (5 µg/ml), WB (1 - 2 µg/ml), |
| Gene ID | 340146 |
|---|---|
| Other Names | SLC35D3, Frc, fringe-like 1, FRCL1, BA55K22.3 |
| Target/Specificity | Human SLC35D3. At least two isoforms of SLC35D3 are known to exist; this antibody will recognize both isoforms. SLC35D3 antibody is predicted to not cross-react with SLC35D1 or SLC35D2. |
| Reconstitution & Storage | PBS, 0.02% sodium azide. Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Precautions | SLC35D3 / FRCL1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLC35D3 (HGNC:15621) |
|---|---|
| Function | Probable UDP-glucose transmembrane transporter involved in UDP-glucose transport from the cytosol to the lumen of synaptic vesicles (PubMed:34269178). It is involved in platelet dense granules maturation (By similarity). |
| Cellular Location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Early endosome membrane {ECO:0000250|UniProtKB:Q8BGF8}; Multi-pass membrane protein. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8BGF8}; Multi-pass membrane protein. Note=Active at early endosome membrane in the biosynthesis of mature platelet-dense granules {ECO:0000250|UniProtKB:Q8BGF8} |

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Provided below are standard protocols that you may find useful for product applications.
Background
May play a role in hemostasis as a regulator of the biosynthesis of platelet-dense granules.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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