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STAT5A Antibody (clone 9F7)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, FC |
|---|---|
| Primary Accession | P42229 |
| Other Accession | 6776 |
| Reactivity | Human, Rat, Monkey, Dog |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Clone Names | 9F7 |
| Calculated MW | 90647 Da |
| Dilution | Flo (1:100), IF (1:100), IHC-P (10 µg/ml), WB (1:500 - 1:2000), |
| Gene ID | 6776 |
|---|---|
| Other Names | STAT5A, MGF, STAT5 |
| Target/Specificity | Human STAT5A / STAT5 |
| Reconstitution & Storage | PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing. |
| Precautions | STAT5A Antibody (clone 9F7) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | STAT5A |
|---|---|
| Synonyms | STAT5 |
| Function | Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL- induced transcription. Regulates the expression of milk proteins during lactation. |
| Cellular Location | Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation |
| Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.
References
Hou J.,et al.Immunity 2:321-329(1995).
Lin J.X.,et al.Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.
Tan D.,et al.Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
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