MXRA5 Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, E |
---|---|
Primary Accession | Q9NR99 |
Other Accession | 25878 |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 312150 Da |
Dilution | IHC-P (5 µg/ml), |
Gene ID | 25878 |
---|---|
Other Names | MXRA5, Adlican |
Target/Specificity | Human MXRA5. |
Reconstitution & Storage | Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing. |
Precautions | MXRA5 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MXRA5 |
---|---|
Function | In kidney, has anti-inflammatory and anti-fibrotic properties by limiting the induction of chemokines, fibronectin and collagen expression in response to TGB1 and pro-inflammatory stimuli. |
Cellular Location | Secreted |
Tissue Location | Detected in placenta (at protein level) (PubMed:32337544). Detected in cerebrospinal fluid and fibroblasts (at protein level) (PubMed:25326458, PubMed:36213313). Highly expressed in kidney, also detected on liver and spleen (PubMed:27599751). Expressed by proximal tubular cells of the kidney (at protein level) (PubMed:27599751). Expression highly increases during chronic kidney disease and autosomal dominant polycystic kidney disease, where is detected in cysts (PubMed:27599751). |
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Provided below are standard protocols that you may find useful for product applications.
References
Crowl R.M.,et al.Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
Chondrogianni N.,et al.Biogerontology 5:401-409(2004).
Ross M.T.,et al.Nature 434:325-337(2005).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Xiong D.,et al.Carcinogenesis 33:1797-1805(2012).
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