MXRA5 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, IHC-F, IF, ICC |
---|---|
Primary Accession | Q9NR99 |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 312150 Da |
Gene ID | 25878 |
---|---|
Other Names | Matrix-remodeling-associated protein 5, Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan, Adlican, MXRA5 |
Dilution | Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | MXRA5 |
---|---|
Function | In kidney, has anti-inflammatory and anti-fibrotic properties by limiting the induction of chemokines, fibronectin and collagen expression in response to TGB1 and pro-inflammatory stimuli. |
Cellular Location | Secreted |
Tissue Location | Detected in placenta (at protein level) (PubMed:32337544). Detected in cerebrospinal fluid and fibroblasts (at protein level) (PubMed:25326458, PubMed:36213313). Highly expressed in kidney, also detected on liver and spleen (PubMed:27599751). Expressed by proximal tubular cells of the kidney (at protein level) (PubMed:27599751). Expression highly increases during chronic kidney disease and autosomal dominant polycystic kidney disease, where is detected in cysts (PubMed:27599751). |
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