Anti-MRGD / MRGPRD Antibody (Cytoplasmic Domain)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | Q8TDS7 |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 36118 Da |
Dilution | IHC-P (10 µg/ml) |
Gene ID | 116512 |
---|---|
Alias Symbol | MRGPRD |
Other Names | MRGPRD, Beta-alanine receptor, MRGD, MAS-related GPR, member D, TGR7 |
Target/Specificity | Human MRGPRD. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-MRGD / MRGPRD Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MRGPRD |
---|---|
Synonyms | MRGD |
Function | May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G- protein G(q) and G(i). |
Cellular Location | Cell membrane; Multi-pass membrane protein Note=Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine |
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