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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-GPR68 / OGR1 Antibody (Extracellular Domain)
Anti-GPR68 / OGR1 Antibody (Extracellular Domain)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | Q15743 |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 41077 Da |
| Dilution | IHC-P (1.25 µg/ml) |
| Gene ID | 8111 |
|---|---|
| Alias Symbol | GPR68 |
| Other Names | GPR68, Brgrb, G protein-coupled receptor 68, G-protein coupled receptor 68, OGR1, Brgr1, GPR12A, OGR-1 |
| Target/Specificity | Human GPR68. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-GPR68 / OGR1 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GPR68 |
|---|---|
| Synonyms | OGR1 |
| Function | Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Also functions as a metastasis suppressor gene in prostate cancer (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Location | Found at low level in a wide range of tissues, but significantly expressed in lung, kidney, bone and nervous system |
Research Areas
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Application Protocols
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$ 467.50
Cat# ALS17540
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