Anti-GPR68 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IF |
---|---|
Primary Accession | Q15743 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 41077 Da |
Gene ID | 8111 |
---|---|
Other Names | OGR1; Ovarian cancer G-protein coupled receptor 1; OGR-1; G-protein coupled receptor 68; GPR12A; Sphingosylphosphorylcholine receptor |
Target/Specificity | Recognizes endogenous levels of GPR68 protein. |
Dilution | WB~~1/500 - 1/1000 IF~~1/50 - 1/200 |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | GPR68 |
---|---|
Synonyms | OGR1 |
Function | Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Also functions as a metastasis suppressor gene in prostate cancer (By similarity). |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | Found at low level in a wide range of tissues, but significantly expressed in lung, kidney, bone and nervous system |

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Provided below are standard protocols that you may find useful for product applications.
Background
Rabbit polyclonal antibody to GPR68

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