Anti-KCNMB2 Antibody (Internal)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IP |
---|---|
Primary Accession | Q9Y691 |
Predicted | Human, Mouse, Rat, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 27130 Da |
Dilution | IHC-P (1:100), IP (1:10 - 1:100), WB (1:500 - 1:1000) |
Gene ID | 10242 |
---|---|
Alias Symbol | KCNMB2 |
Other Names | KCNMB2, BK beta 2, HKCNMB2, Hbeta2, Maxi K beta 2, HCG1646471, K(VCA)beta-2, MaxiK channel beta 2 subunit, SLO-BETA2, BK channel subunit beta-2, BKbeta2, HBETA3, Maxi K channel subunit beta-2, Slo-beta-2 |
Target/Specificity | Recognizes endogenous levels of KCNMB2 protein. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-KCNMB2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | KCNMB2 |
---|---|
Function | Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons. |
Cellular Location | Membrane; Multi-pass membrane protein. |
Tissue Location | Expressed in kidney, heart and brain. Highly expressed in ovary. Expressed at low level in other tissues |
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