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WBP2 Antibody (C-term)
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q969T9 |
| Reactivity | Human, Mouse |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG1 |
| Clone/Animal Names | 932CT1.3.7 |
| Calculated MW | 28087 Da |
| Gene ID | 23558 |
|---|---|
| Other Names | WW domain-binding protein 2, WBP-2, WBP2 |
| Target/Specificity | This WBP2 antibody is generated from a mouse immunized with a recombinant protein between 1-261 amino acids from the C-terminal region of human WBP2. |
| Dilution | WB~~1:2000 E~~Use at an assay dependent concentration. |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | WBP2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | WBP2 (HGNC:12738) |
|---|---|
| Function | Acts as a transcriptional coactivator of estrogen and progesterone receptors (ESR1 and PGR) upon hormone activation (PubMed:16772533). In presence of estrogen, binds to ESR1-responsive promoters (PubMed:16772533). Synergizes with YAP1 to enhance PGR activity (PubMed:16772533). Modulates expression of post-synaptic scaffolding proteins via regulation of ESR1, ESR2 and PGR (By similarity). |
| Cellular Location | Cytoplasm. Nucleus. Note=Translocates from cytoplasm to nucleus when phosphorylated. |
| Tissue Location | Ubiquitous. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Chen H.I.,et al.J. Biol. Chem. 272:17070-17077(1997).
Pirozzi G.,et al.J. Biol. Chem. 272:14611-14616(1997).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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