CAPNS1 Antibody
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P04632 |
Reactivity | Hamster, Rabbit |
Host | Mouse |
Clonality | monoclonal |
Isotype | IgG2b,κ |
Clone/Animal Names | 2190CT339.12.2 |
Calculated MW | 28316 Da |
Gene ID | 826 |
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Other Names | Calpain small subunit 1, CSS1, Calcium-activated neutral proteinase small subunit, CANP small subunit, Calcium-dependent protease small subunit, CDPS, Calcium-dependent protease small subunit 1, Calpain regulatory subunit, CAPNS1, CAPN4, CAPNS |
Target/Specificity | This CAPNS1 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 1-323 amino acids from the human region of human CAPNS1. |
Dilution | WB~~1:4000 |
Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CAPNS1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CAPNS1 |
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Synonyms | CAPN4, CAPNS |
Function | Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Essential for embryonic development (By similarity). |
Cellular Location | Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon calcium binding. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
References
Ohno S.,et al.Nucleic Acids Res. 14:5559-5559(1986).
Miyake S.,et al.Nucleic Acids Res. 14:8805-8817(1986).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Kalnine N.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Grimwood J.,et al.Nature 428:529-535(2004).
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