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Anti-Arginase I (ARG1) Antibody
Our Anti-Arginase I (ARG1) primary antibody from PhosphoSolutions is chicken polyclonal. It detects
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Application 
| WB |
|---|---|
| Primary Accession | P07824 |
| Reactivity | Bovine, Chicken |
| Host | Chicken |
| Clonality | Polyclonal |
| Isotype | IgY |
| Calculated MW | 34973 Da |
| Gene ID | 29221 |
|---|---|
| Other Names | A I antibody, Al antibody, ARG 1 antibody, arg1 antibody, ARGI1_HUMAN antibody, Arginase 1 antibody, Arginase liver antibody, Arginase type I antibody, Arginase liver antibody, Arginase-1 antibody, Arginase1 antibody, Liver type arginase antibody, Liver-type arginase antibody, Type I arginase antibody |
| Target/Specificity | Arginase I, a cytosolic enzyme, is highly expressed in the liver and is a component of the urea cycle (Jenkinson et al, 1996). There are two isoforms of arginase, both catalyze the conversion of arginine to ornithine and urea, but differ based on subcellular localization, tissue distribution, and enzymatic properties (Jenkinson et al, 1996). Arginase I has been identified in macrophages in response to various pathogen exposures causing an upregulation of inducible nitric oxide synthase, iNOS, yielding increased levels of nitric oxide (Morris et al, 1998) and inflammation (Poljakovic et al, 2007). |
| Format | Total IgY fraction |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Anti-Arginase I (ARG1) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Shipping | Blue Ice |
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Provided below are standard protocols that you may find useful for product applications.
Background
Arginase I, a cytosolic enzyme, is highly expressed in the liver and is a component of the urea cycle (Jenkinson et al, 1996). There are two isoforms of arginase, both catalyze the conversion of arginine to ornithine and urea, but differ based on subcellular localization, tissue distribution, and enzymatic properties (Jenkinson et al, 1996). Arginase I has been identified in macrophages in response to various pathogen exposures causing an upregulation of inducible nitric oxide synthase, iNOS, yielding increased levels of nitric oxide (Morris et al, 1998) and inflammation (Poljakovic et al, 2007).
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