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Anti-CD75 (Transferrin receptor) Antibody
Our Anti-CD75 (Transferrin receptor) mouse monoclonal primary antibody from PhosphoSolutions is prod
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- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P15907 |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgM |
| Clone Names | LN1 |
| Calculated MW | 46605 Da |
| Gene ID | 6480 |
|---|---|
| Other Names | 6 sialyltransferase antibody, 6-sialyltransferase 1 antibody, 6-ST 1 antibody, Alpha 2 antibody, Alpha 2, 6 ST 1 antibody, Alpha 2, 6 ST antibody, B cell antigen CD75 antibody, B-cell antigen CD75 antibody, Beta galactoside alpha 2, 6 sialyltransferase 1 antibody, Beta-galactoside alpha-2 antibody, CMP N acetylneuraminate beta galactosamide alpha 2, 6 sialyltransferase 1 antibody, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2 antibody, MGC48859 antibody, Sialyltransferase 1 (beta galactoside alpha 2, 6 sialyltransferase) antibody, Sialyltransferase 1 antibody, SIAT1 antibody, SIAT1_HUMAN antibody, ST6 beta galactosamide alpha 2, 6 sialyltranferase 1 antibody, ST6Gal I antibody, ST6GAL1 antibody, ST6GalI antibody, ST6N antibody |
| Target/Specificity | CD75, also known as β-galactoside α2,6-sialyltransferase, is a specific carbohydrate antigen that is predominantly expressed on B cell lymphocytes. β-galactoside α2,6-sialyltransferase is an enzyme that catalyzes the addition of sialic acid to growing carbohydrate chains of glycoproteins (Guy, K., et al, 1991). CD75 is a major component of the lymphoid cell surface that serves as a ligand for cell adhesion molecules (Paulson, J.C., et al, 1989). The LN-1 clone reacts positively with red blood cell precursors of the bone marrow, ciliated epithelial cells of the bronchus, distal tubular cells of the kidney, and ductal cells from several organs including the breast and prostate (Epstein, A.L., et al, 1984). CD75 has been shown to be superior to other B cell markers in detecting lymphocyte predominant cells through their cytoplasmic and membraneous staining, especially in typical nodular lymphocyte-predominant Hodgkin lymphoma patterns (Carbone, A., et al, 2014). |
| Format | Protein L purified |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Anti-CD75 (Transferrin receptor) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Shipping | Blue Ice |
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Provided below are standard protocols that you may find useful for product applications.
Background
CD75, also known as β-galactoside α2,6-sialyltransferase, is a specific carbohydrate antigen that is predominantly expressed on B cell lymphocytes. β-galactoside α2,6-sialyltransferase is an enzyme that catalyzes the addition of sialic acid to growing carbohydrate chains of glycoproteins (Guy, K., et al, 1991). CD75 is a major component of the lymphoid cell surface that serves as a ligand for cell adhesion molecules (Paulson, J.C., et al, 1989). The LN-1 clone reacts positively with red blood cell precursors of the bone marrow, ciliated epithelial cells of the bronchus, distal tubular cells of the kidney, and ductal cells from several organs including the breast and prostate (Epstein, A.L., et al, 1984). CD75 has been shown to be superior to other B cell markers in detecting lymphocyte predominant cells through their cytoplasmic and membraneous staining, especially in typical nodular lymphocyte-predominant Hodgkin lymphoma patterns (Carbone, A., et al, 2014).
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