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Anti-Calcitonin Gene Related Peptide (CGRP) Antibody
Our Anti-Calcitonin Gene Related Peptide (CGRP) primary antibody from PhosphoSolutions is mouse mono
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P01256 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Clone Names | 4901 |
| Calculated MW | 13948 Da |
| Gene ID | 24241 |
|---|---|
| Other Names | Calcitonin/calcitonin related polypeptide alpha antibody, Alpha type CGRP antibody, Beta type CGRP antibody, CALC1 antibody, CALC2 antibody, CALCA antibody, CALCB antibody, Calcitonin 1 antibody, Calcitonin 2 antibody, Calcitonin gene related peptide I antibody, Calcitonin gene related peptide II antibody, Calcitonin related polypeptide alpha antibody, Calcitonin related polypeptide beta antibody, CGRP antibody, CGRP I antibody, CGRP II antibody, CGRP1 antibody, CGRP2 antibody, CT antibody, Katacalcin antibody, KC antibody |
| Target/Specificity | Calcitonin Gene Related Peptide [CGRP] is a 37 amino acid peptide and is the most potent endogenous vasodilator currently known (Brain et al.,1985). CGRP is primarily produced in nervous tissue, however, its receptors are expressed throughout the body. CGRP is also strongly implicated in the vasodilatory effect of endogenous cannabinoid anandamide in the brain. This effect was found to be antagonized by capsazepine. CGRP is also currently a major target of research in regards to factors effecting the onset of migraine headaches (Edvinsson L., 2003). CGRP antibodies have been used successfully in immunoneutralization (Wong et al., 1993). |
| Format | Protein G Purified |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Anti-Calcitonin Gene Related Peptide (CGRP) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Shipping | Blue Ice |
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Provided below are standard protocols that you may find useful for product applications.
Background
Calcitonin Gene Related Peptide [CGRP] is a 37 amino acid peptide and is the most potent endogenous vasodilator currently known (Brain et al.,1985). CGRP is primarily produced in nervous tissue, however, its receptors are expressed throughout the body. CGRP is also strongly implicated in the vasodilatory effect of endogenous cannabinoid anandamide in the brain. This effect was found to be antagonized by capsazepine. CGRP is also currently a major target of research in regards to factors effecting the onset of migraine headaches (Edvinsson L., 2003). CGRP antibodies have been used successfully in immunoneutralization (Wong et al., 1993).
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