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LCN1 Antibody

Purified Mouse Monoclonal Antibody

     
  • WB - LCN1 Antibody AO1270a
    Figure 1: Western blot analysis using LCN1 mouse mAb against HEK293 (1) and
    LCN1-hIgGFc transfected HEK293 cell lysate (2).
    detail
  • IHC - LCN1 Antibody AO1270a
    Figure 2: Immunohistochemical analysis of paraffin-embedded human Prostate tissues using LCN1 mouse mAb
    detail
  • IF - LCN1 Antibody AO1270a
    Figure 3: Confocal immunofluorescence analysis of methanol-fixed HEK293 cells trasfected with LCN1-hIgGFc using LCN1 mouse mAb(green), showing membrane localization. Blue: DRAQ5 fluorescent DNA dye.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, ICC, E
Primary Accession P31025
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 10B10
Isotype IgG1
Calculated MW 19.2kDa
Description LCN1: lipocalin 1 (tear prealbumin), also known as TP, PMFA, VEGP. Entrez Protein: NP_002288. The protein belongs to the lipocalin family. Lipocalins are a group of extracellular proteins that are able to bind lipophiles by enclosure within their structures to minimize solvent contact. This protein may bind hydrophobic ligands and inhibit cysteine proteinases. It may also play a role in taste reception and could be necessary for the concentration and delivery of sapid molecules in the gustatory system.
Immunogen Purified recombinant fragment of LCN1 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 3933
Other Names Lipocalin-1, Tear lipocalin, Tlc, Tear prealbumin, TP, Von Ebner gland protein, VEG protein, LCN1, VEGP
Dilution WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
IF~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLCN1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LCN1
Synonyms VEGP
Function Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket.
Cellular Location Secreted.
Tissue Location Mainly expressed in lachrymal and salivary glands. Also expressed in the prostate
Citations (0)
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References

1. Adv Exp Med Biol. 2002;506(Pt A):555-65. 2. J Autoimmun. 2005 Nov;25(3):229-34.

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$ 325.00
Cat# AO1270a
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