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SCGB2A2 Antibody

Purified Mouse Monoclonal Antibody

     
  • WB - SCGB2A2 Antibody AO1478a
    Figure 1: Western blot analysis using SCGB2A2 mAb against human SCGB2A2 (AA: 2-93) recombinant protein. (Expected MW is 35.8 kDa)
    detail
  • IHC - SCGB2A2 Antibody AO1478a
    Figure 2: Immunohistochemical analysis of paraffin-embedded mammary cancer tissues using SCGB2A2 mouse mAb with DAB staining.
    detail
  • IF - SCGB2A2 Antibody AO1478a
    Figure 3: Immunofluorescence analysis of Hela cells using SCGB2A2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
    detail
  • FC - SCGB2A2 Antibody AO1478a
    Figure 4: Flow cytometric analysis of SK-BR-3 cells using SCGB2A2 mouse mAb (green) and negative control (purple).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, FC, ICC, E
Primary Accession Q13296
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 3C8
Isotype IgG1
Calculated MW 11kDa
Description Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.Tissue specificity: Mammary gland specific. Over-expressed in breast cancer.
Immunogen Purified recombinant fragment of human SCGB2A2 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 4250
Other Names Mammaglobin-A, Mammaglobin-1, Secretoglobin family 2A member 2, SCGB2A2, MGB1, UGB2
Dilution WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
IF~~1/200 - 1/1000
FC~~1/200 - 1/400
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSCGB2A2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SCGB2A2
Synonyms MGB1, UGB2
Cellular Location Secreted.
Tissue Location Mammary gland specific. Over-expressed in breast cancer
Citations (0)
citation

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References

1. Ann Oncol. 2006 Jun;17 Suppl 7:vii41-5. 2. Mod Pathol. 2007 Feb;20(2):208-14.

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$ 325.00
Cat# AO1478a
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