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CRP Antibody

Purified Mouse Monoclonal Antibody

     
  • E - CRP Antibody AO1685a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

    detail
  • WB - CRP Antibody AO1685a
    Figure 1: Western blot analysis using CRP mAb against human CRP recombinant protein. ( AA: 1-224, Expected MW is 51 kDa)
    detail
  • FC - CRP Antibody AO1685a
    Figure 2: Flow cytometric analysis of MCF-7 cells using CRP mouse mAb (green) and negative control (red).
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  • IHC - CRP Antibody AO1685a
    Figure 3: Immunohistochemical analysis of paraffin-embedded liver cancer tissues using CRP mouse mAb with DAB staining.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, FC, E
Primary Accession P02741
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1G1
Isotype IgG1
Calculated MW 25kDa
Description The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli.
Immunogen Purified recombinant fragment of human CRP expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 1401
Other Names C-reactive protein, C-reactive protein(1-205), CRP, PTX1
Dilution E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCRP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CRP
Synonyms PTX1
Function Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
Cellular Location Secreted.
Tissue Location Found in plasma.
Research Areas
Citations (0)
citation

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References

1. Clin Cardiol. 2010 Nov;33(11):708-14. 2. Mol Cell Biochem. 2011 Jan;347(1-2):183-9.

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$ 385.00
Cat# AO1685a
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