HTR3B
Purified Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, ICC, E |
---|---|
Primary Accession | O95264 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 2H9H5 |
Isotype | Mouse IgG2b |
Calculated MW | 50.3kDa |
Immunogen | Purified recombinant fragment of human HTR3B (AA: extra 23-150) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Gene ID | 9177 |
---|---|
Other Names | 5-HT3B |
Dilution | E~~ 1/10000 WB~~ 1/500 - 1/2000 FCM~~1/200 - 1/400 ICC~~ 1/100 - 1/500 |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | HTR3B is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HTR3B (HGNC:5298) |
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Function | Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation- selective channel complexes, which when activated cause fast, depolarizing responses in neurons. |
Cellular Location | Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Presumably retained within the endoplasmic reticulum unless complexed with HTR3A |
Tissue Location | Expressed in the brain cortex, in the caudate nucleus, the hippocampus, the thalamus and the amygdala. Detected in the kidney and testis as well as in monocytes of the spleen, small and large intestine, uterus, prostate, ovary and placenta |
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Provided below are standard protocols that you may find useful for product applications.
References
1.Yonsei Med J. 2015 Sep;56(5):1415-20.2.Psychiatry Res. 2014 Sep 30;219(1):235-7.
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