CCDC123 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
---|---|
Primary Accession | Q96ST8 |
Other Accession | NP_116205.3 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 89590 Da |
Antigen Region | 658-687 aa |
Gene ID | 84902 |
---|---|
Other Names | Centrosomal protein of 89 kDa, Cep89, Centrosomal protein 123, Cep123, Coiled-coil domain-containing protein 123, CEP89, CCDC123 |
Target/Specificity | This CCDC123 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 658-687 amino acids from the C-terminal region of human CCDC123. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CCDC123 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CEP89 |
---|---|
Synonyms | CCDC123 |
Function | Required for ciliogenesis. Also plays a role in mitochondrial metabolism where it may modulate complex IV activity. |
Cellular Location | Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Mitochondrion intermembrane space. Note=Localizes to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane |
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Provided below are standard protocols that you may find useful for product applications.
References
Kottgen, A., et al. Nat. Genet. 42(5):376-384(2010)
Chambers, J.C., et al. Nat. Genet. 42(5):373-375(2010)
Hahn, Y., et al. Hum. Genet. 119 (1-2), 169-178 (2006) :
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