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> home > Products > Primary Antibodies > Antibody Collections > Anti-Wnt-Pathway (plus Lgr5) Antibodies > FSTL1 Antibody (C-term)
FSTL1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 3
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, IHC-P, E |
|---|---|
| Primary Accession | Q12841 |
| Other Accession | Q9GKY0, NP_009016.1 |
| Reactivity | Human, Mouse, Rat |
| Predicted | Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 34986 Da |
| Antigen Region | 280-308 aa |
| Gene ID | 11167 |
|---|---|
| Other Names | Follistatin-related protein 1, Follistatin-like protein 1, FSTL1, FRP |
| Target/Specificity | This FSTL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 280-308 amino acids from the C-terminal region of human FSTL1. |
| Dilution | FC~~1:10~50 WB~~1:1000 IHC-P~~1:50~100 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FSTL1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FSTL1 |
|---|---|
| Synonyms | FRP |
| Function | Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation (PubMed:22265692, PubMed:29212066). Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter (By similarity). Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes (By similarity). Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors (PubMed:20054002, PubMed:22265692). |
| Cellular Location | Secreted. |
| Tissue Location | Overexpressed in synovial tissues from rheumatoid arthritis (PubMed:15638044). |
Research Areas
Citations ( 0 )
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Kai, N., et al. Brain Res. 1073-1074, 60-70 (2006) :
Venter, J.C., et al. Science 291(5507):1304-1351(2001)
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$ 150.00
$ 385.00
Cat# AP10534b
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