CEP70 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| FC, WB, IHC-P, E |
|---|---|
| Primary Accession | Q8NHQ1 |
| Other Accession | Q4R7V1, NP_077817.2 |
| Reactivity | Human, Hamster |
| Predicted | Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 69752 Da |
| Antigen Region | 309-338 aa |
| Gene ID | 80321 |
|---|---|
| Other Names | Centrosomal protein of 70 kDa, Cep70, p10-binding protein, CEP70, BITE |
| Target/Specificity | This CEP70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-338 amino acids from the Central region of human CEP70. |
| Dilution | FC~~1:10~50 WB~~1:1000 IHC-P~~1:50~100 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CEP70 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CEP70 |
|---|---|
| Synonyms | BITE |
| Function | Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle. |
| Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localized at the center of the radial microtubule array in interphase and at the spindle poles during various stages of mitosis |

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Provided below are standard protocols that you may find useful for product applications.
References
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Lim, J., et al. Cell 125(4):801-814(2006)
Petretti, C., et al. EMBO Rep. 7(4):418-424(2006)
Andersen, J.S., et al. Nature 426(6966):570-574(2003)
Casenghi, M., et al. Dev. Cell 5(1):113-125(2003)
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