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CK073 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | Q53FT3 |
| Other Accession | NP_057485.2 |
| Reactivity | Human, Hamster |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 21628 Da |
| Antigen Region | 6-35 aa |
| Gene ID | 51501 |
|---|---|
| Other Names | Protein Hikeshi, C11orf73 |
| Target/Specificity | This CK073 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-35 amino acids from the N-terminal region of human CK073. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CK073 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HIKESHI (HGNC:26938) |
|---|---|
| Synonyms | C11orf73 |
| Function | Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin- dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q9DD02}. Cytoplasm, cytosol. Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
Required for organization and/or function of the secretory apparatus in Clara cells in lung (By similarity).
References
Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)
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